Effects of retinoic acid in the mouse olfactory sensory systems
نویسنده
چکیده
.................................................................................................. 5 SVENSK SAMMANFATTNING .............................................................. 6 PAPERS IN THIS THESIS .......................................................................... 7 ABBREVIATIONS ....................................................................................... 8 INTRODUCTION ....................................................................................... 9 The olfactory systems ............................................................................. 9 The olfactory epithelium .................................................................. 10 The main olfactory bulb and axonal projection map ....................... 16 The accessory olfactory system ........................................................... 22 The vomeronasal epithelium ........................................................... 22 The accessory olfactory bulb and axonal projection map ........... 23 Behavior .............................................................................................. 25 Retinoic acid ........................................................................................... 26 Metabolic pathways of vitamin A................................................... 26 Retinoic acid signaling in the olfactory system ............................ 28 AIMS ........................................................................................................... 30 RESULTS AND DISCUSSION ................................................................ 31 Graded patterns of gene expression correlating with odorant receptor zones. ....................................................................................... 31 Retinoic acid signaling is necessary for postnatal survival of mature olfactory and vomeronasal sensory neurons....................... 34 CONCLUSIONS ........................................................................................ 43 TACK .......................................................................................................... 44 REFERENCES ............................................................................................ 46
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تاریخ انتشار 2007